Elutiq GmbH

Engineering the Future of Orthopedic Care

Through 'in-bone micro-pharmacies' targeting compromised bone biology.

Drug-eluting solutions enabling single-stage treatment of orthopedic infections and bone defects.

1st place at BioRiver 2025 Top 12 MedTech startup at Plug and Play 2026 Galaxy Community Award 2026 winner
Clinical reality in orthopedic infection care

The Clinical Reality

Complex orthopedic infections and large bone defects remain among the most difficult challenges in musculoskeletal medicine. The current standard of care often requires two or more surgical procedures combined with prolonged systemic antibiotic therapy.

This increases operating room utilization, extends recovery timelines, exposes patients to systemic side effects, and significantly increases total episode-of-care costs for hospitals and healthcare systems.

Clinical indications for Elutiq platform

Clinical Indications

Open Fractures (Gustilo II-III): severe traumatic fractures frequently present with contaminated bone defects and a high risk of infection. Effective local infection control combined with structural bone repair is critical for limb salvage.

Chronic Osteomyelitis: persistent bone infections often require multiple surgeries, prolonged hospitalization, and long-term antibiotic therapy, with high recurrence rates and significant healthcare costs.

Periprosthetic Joint Infection: infections around joint replacements are among the most devastating complications in orthopedic surgery, frequently requiring staged revision procedures and extended treatment timelines.

Infected Non-Union: combined failure of bone healing combined with infection represents a complex clinical scenario where infection eradication and biological bone regeneration must be addressed simultaneously.

Elutiq platform approach for orthopedic surgery

Our Platform Approach

Elutiq GmbH is transforming orthopedic surgery by creating 'in-bone micro-pharmacies', a platform designed for scalable regulatory pathways and broad orthopedic indications, where surgeons can balance infection management, structural repair, and regeneration within a single treatment strategy.

We combine advanced nanomedicine and pharmacological delivery technologies with clinically proven allograft biology, creating solutions aligned with surgeon workflow, hospital economics, and regulatory feasibility.

Why now

The Shift Toward Single-Stage Solutions

Orthopedic infections and complex bone defects are rising globally due to aging populations, increasing trauma cases, and the rapid growth of joint replacement surgeries. Antimicrobial resistance and hospital cost pressures are forcing a shift toward more efficient surgical solutions. Elutiq's drug-eluting bone graft platform addresses this convergence by enabling infection control and bone regeneration within a single surgical strategy.

Clinical and Institutional Validation

Elutiq collaborates with leading academic and clinical institutions including RWTH Aachen University and University Hospital Aachen. Early engagement with orthopedic surgeons and trauma centers in Europe and the United States supports clinical translation and alignment with real surgical workflows.

Innovation Platform

Elutiq merges nanomedicine and pharmacological technologies with clinically proven allograft biology to replace costly two-stage procedures with one-stage treatment where infection management and regeneration happen together.

US economy

Economic Value of Single-Stage Treatment

Adoption is driven by total episode cost, not implant price. Elutiq is designed to reduce total episode cost by eliminating downstream procedures and operational inefficiencies.

Current treatment pathway

$6-10K

Adjunct material.

$25-45K

Staged procedures structural cost.

Operational inefficiency

OR time | LOS | Readmissions

$30-50K

Total episode cost.

$100-120K

Total cost range including revision/s

Elutiq single-stage platform

~$7.5K

Single procedure.

No staged procedures

Reduced OR time | Reduced LOS

Lower total episode cost

Operational efficiency can support hospital margin expansion.

No new reimbursement codes required

OsteoFlux™ is aligned within existing US MS-DRG.

Margin expansion is driven by operational efficiency, not reimbursement change.

The single-stage platform targets the downstream costs created by repeated procedures, length of stay, readmissions, and operating room inefficiency.